The CHERISH network has expertise and insight in Budget Impact Analysis, Costing, Health-Related Quality of Life, Resource Utilization, and Recommended Health Economic references. Click below to find out more.

The National Drug Abuse Clinical Trials Network (CTN) study, CTN-0032: HIV Rapid Testing and Counseling (NCT00809445), was conducted at 12 substance abuse treatment programs in 2009, and demonstrated efficacy, feasibility / acceptability, and cost-effectiveness of on-site rapid HIV testing compared to off-site referral with no additional benefit for on-site pre-test HIV sexual risk-reduction counseling.  As part of a joint effort between the CTN and the Substance Abuse Mental Health Services Administration’s Addiction Technology Transfer Network, the CTN-0032 study team produced research-based products designed specifically for substance abuse treatment providers. One product was a Microsoft Excel spreadsheet tool designed to assist substance use treatment programs in creating a budget for delivering onsite rapid HIV testing services.

Compatible with Microsoft Excel 2003 or before: CTN 0032 Blending_03 or before.xls

Compatible with Microsoft Excel 2007 or later: CTN 0032 Blending_07 or later.xlsx


Assessment Name Description Link
DATCAP The Drug Abuse Treatment Cost Analysis Program Organizes program cost data across standard categories of resources (e.g. personnel, buildings and facilities, supplies and materials, and miscellaneous) and can be used for a variety of treatment interventions, workplace programs, and other behavioral health programs to estimate total annual program cost and average annual cost per client.
SASCAP Substance Abuse Services Cost Analysis Program Uses program data to estimate service-level costs for services such as initial patient assessment and treatment planning, initial medical services, counseling, ongoing medical services, case management, quality assurance, and methadone dosing.

Health-Related Quality of Life

Generic Health-Related Quality of Life Instruments for Calculating Preference or Utility Weights
Instrument Name Description Link
EQ-5D EuroQol-5D EQ-5D is a standardized, 5-dimensional, HRQoL instrument developed by the EuroQol Group. The EQ-5D consists of a descriptive system and the EQ visual analog scale (VAS). The descriptive system is mapped to a health-state index value, which can be used in the calcluation of QALYs. A health-state value of 0 represents death, 1 represents perfect health, and values below zero represent states perceived to be worse than death.
SF-6D® Short Form 6D® The SF-6D provides a means for mapping the SF-36 and SF-12, version 2, to to a health-state index value, which can be used in the calcluation of QALYs. Health-state values range from 0 (death) to 1 (perfect health).
QWB-SA Quality of Well-Being Scale — Self Administered The QWB is a preference-weighted measure combining three dimensions of functioning with a measure of symptoms and problems to produce a point-in-time expression of well-being that runs from 0 (death) to 1 (perfect health), which can then be used to calculate QALYs.
15D 15-dimensional The 15D is a 15-dimensional, HRQoL instrument that can be mapped to a health-state index value for calculating QALYs. Health-state values range from 0 (death) to 1 (perfect health).
HUI® Health Utilities Index® The HUI® measurement system is a comprehensive system for measuring health status, health-related quality of life, and producing a health-state index value for calculating QALYs, where 0 represents death, and 1 represents perfect health.
ReQoL Recovering Quality of Life Questionnaire ReQoL is a Patient Reported Outcome Measure developed to assess the quality of life for people with different mental health conditions. Research is ongoing to develop preference weights for use in health economic analysis.

Resource Utilization

Assessment Name Description Link
ASI Addiction Severity Index

The ASI is a semi-structured interview designed to address seven potential problem areas in individuals with a substance use disorder: medical status, employment and support, drug use, alcohol use, legal status, family/social status, and psychiatric status
Economic Form 90 Economic Form 90

Designed to measure changes from baseline on key economic outcomes following treatment for alcohol use disorder
NMOS Non-Study Medical and Other Services

Collects individual-level data on substance use disorder, mental health, and physical health services received outside of the study-specific treatment setting. It has been flexibly adapted to the needs of different study interventions and populations.
GAIN Global Appraisal of Individual Needs

Collects individual-level information on the utilization of substance use disorder, mental health, physical health, community, and social services, as well as criminal justice resources.
  • Drummond MF. Methods for the Economic Evaluation of Health Care Programmes. Oxford university press; 2005. ISBN 978-019-852944-6 | ISBN 978-019-852945-3
  • Muennig P, Bounthavong M. Cost-Effectiveness Analysis in Health: A Practical Approach, 3rd Edition. John Wiley & Sons, Inc.; 2007. ISBN 978-1-119-01126-2
  • Glick HA, Doshi JA, Sonnad SS, Polsky D. Economic evaluation in clinical trials. Oxford University Press; 2014. ISBN 978-0-199-68502-8
  • Neumann PJ, Sanders GD, Russell LB, Siegel JE, Ganiats TG. Cost-Effectiveness in Health and Medicine. 2nd ed. New York, NY: Oxford University Press; 2017. ISBN 978-0-190-49293-9
  • University of Pennsylvania, Health Services Research Unit (resources include presentations from past lectures, Stata programs, etc.):
  • State Health Practice Database for Research:
  • The Tufts Medical Center Cost-Effectiveness Analysis Registry:
  • Guidance on selecting the most appropriate price index for adjusting health expenditures or costs for inflation:

Dunn A, Grosse SD, Zuvekas SH. Adjusting Health Expenditures for Inflation: A Review of Measures for Health Services Research in the United States. Health Serv Res. 2016 Nov 21. doi: 10.1111/1475-6773.12612. [Epub ahead of print]

  • Guidance on selecting appropriate monetary conversation factors / unit costs for use in economic analysis are available here:

McCollister K, Yang X, Sayed B, French MT, Leff JA, Schackman BR. Monetary Conversion Factors for Economic Evaluations of Substance Use Disorders. Journal of Substance Abuse Treatment. 2017;81:25-34.